Recombinant Human CD147/Basigin Protein (His Tag)
Product Specifications
Background
Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.
Abbreviation
CD147; Basigin
Synonyms
5F7; BSG; Basigin; CD147; Collagenase Stimulatory Factor; EMMPRIN; Extracellular Matrix Metalloproteinase Inducer; Leukocyte Activation Antigen M6; OK Blood Group Antigen; TCSF; Tumor Cell-Derived Collagenase Stimulatory Factor
UniProt
P35613
Accession Number
P35613-2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala22-His205
Field of Research
Immunology, Neuroscience, Cancer, Metabolism, Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
21.2 kDa
Observed Molecular Weight
30-40 kDa
Species
Human
Available Sizes
Documents
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