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Recombinant Human CD147/Basigin Protein (His Tag)

Product Specifications

Background

Extracellular Matrix Metalloproteinase Inducer (EMMPRIN) belongs to the immunoglobulin superfamily, which has the homology to both the immunoglobulin V domain and MHC class II antigen β-chain. EMMPRIN is a transmembrane glycoprotein with different forms, resulting from different modes of glycosylation and N-terminal sequence variants. EMMPRIN can be expressed in breast cancer, oral squamous cell carcinoma, glioma, lymphoma, lung, bladder, and melanoma carcinomas cells. EMMPRIN promotes invasion, metastasis, growth, and survival of malignants cells, serves as a receptor for extracellular cyclophilinthe, may play a role in signal transduction.

Abbreviation

CD147; Basigin

Synonyms

5F7; BSG; Basigin; CD147; Collagenase Stimulatory Factor; EMMPRIN; Extracellular Matrix Metalloproteinase Inducer; Leukocyte Activation Antigen M6; OK Blood Group Antigen; TCSF; Tumor Cell-Derived Collagenase Stimulatory Factor

UniProt

P35613

Accession Number

P35613-2

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ala22-His205

Field of Research

Immunology, Neuroscience, Cancer, Metabolism, Cardiovascular

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

21.2 kDa

Observed Molecular Weight

30-40 kDa

Species

Human

Available Sizes

Frequently Asked Questions

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