Recombinant Human HSP40/DNAJB1 Protein (His Tag)
Product Specifications
Background
DnaJ Homolog Subfamily B Member 1 (DNAJB1) is a member of the heat shock protein family. Heat shock proteins (HSPs) are a highly conserved family of stress response proteins. HSPs function primarily as molecular chaperones, facilitating the folding of other cellular proteins, preventing protein aggregation, or targeting improperly folded proteins to specific degradative pathways. DNAJB1 regulates cellular processes by aiding in the folding, transport and assembly. DNAJB1 contains a J-domain which controls interaction with the ATPase domain of DnaK. DNAJB1 interacts with HSP70 and can stimulate its ATPase activity. In addition, DNAJB1 stimulates the association between HSC70 and HIP.
Abbreviation
HSP40; DNAJB1
Synonyms
DNAJ1; DNAJB1; DnaJ Homolog Subfamily B Member 1; DnaJ Protein Homolog 1; HDJ1; HSP40; HSPF1; Heat Shock 40 kDa Protein 1; Heat Shock Protein 40; Human DnaJ Protein 1; hDj-1
UniProt
P25685
Accession Number
P25685
Expression System
E.coli
Tag
C-His
Sequence
Gly2-Ile340
Field of Research
Signal Transduction
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/v5888g
Product MSDS
https://789.bio/eb/iXLuvP
Calculated Molecular Weight
39.1 kDa
Observed Molecular Weight
38 kDa
Species
Human
Available Sizes
Curated Selection
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