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Recombinant Human DPP3 Protein (His Tag)

Product Specifications

Background

Dipeptidyl peptidase 3 (DPP3), is a member of the S9B family in clan SC of the serine proteases. DPP3 has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) . It releases an N-terminal dipeptide from a peptide comprising four or more residues, with broad specificity and also acts on dipeptidyl 2-naphthylamides.Increased activity of this protein has a relationship with endometrial and ovarian cancers.

Abbreviation

DPP3

Synonyms

DPP3; Dipeptidyl aminopeptidase III; Dipeptidyl arylamidase III; Dipeptidyl peptidase 3; Dipeptidyl peptidase III; Enkephalinase B

UniProt

Q9NY33

Accession Number

Q9NY33

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Ala737

Field of Research

Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

84.8 kDa

Observed Molecular Weight

70-90 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 25mM Tris-HCl, 10mM NaCl, 2mM DTT, 0.05% Tween 80, 20% Glycerol, pH 8.0.

Species

Human

Available Sizes

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