Recombinant Human Desmin Protein (His Tag)
Product Specifications
Background
Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is the main intermediate filament in mature skeletal, cardiac and smooth-muscle cells. DES founctions as homopolymers to form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. .Defects in DES are cause of the myopathy myofibrillar type 1, cardiomyopathy dilated type 1I, and neurogenic scapuloperoneal syndrome Kaeser type.
Abbreviation
Desmin
Synonyms
DES; Desmin
UniProt
P17661
Accession Number
P17661
Expression System
E.coli
Tag
N-His
Sequence
Val261-Leu470
Field of Research
Signal Transduction; Cardiovascular; Cancer; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/lgvayp
Product MSDS
https://789.bio/eb/4KqDGC
Calculated Molecular Weight
26.7 kDa
Observed Molecular Weight
30 kDa
Species
Human
Available Sizes
Curated Selection
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