Recombinant Human DCUN1D1 Protein (His Tag)
Product Specifications
Background
DCN1-Like Protein 1 is a protein containing 1 DCUN1 domain and 1 UBA-like domain. DCN1-Like Protein 1 contains part of an E3 Ubiquitin Ligase Complex for Neddylation. It is required for Neddylation of Cullin components of E3 Cullin-RING Ubiquitin Ligase complexes. It enhances the rate of Cullins Neddylation. DCN1-Like Protein 1 recruits the NEDD8-charged E2 Enzyme to the Cullin component. DCUN1D1 is involved in the release of inhibitory effects of CAND1 on the Cullin-RING Ligase E3 complex assembly and activity. It acts also as an oncogene facilitating malignant transformation and carcinogenic progression.
Abbreviation
DCUN1D1
Synonyms
DCN1-Like Protein 1; DCUN1 Domain-Containing Protein 1; DCUN1D1; DCUN1L1; Defective in Cullin Neddylation Protein 1-Like Protein 1; RP42; SCCRO; Squamous Cell Carcinoma-Related Oncogene
UniProt
Q96GG9
Accession Number
Q96GG9
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Val259
Field of Research
Cell biology; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
32.3 kDa
Observed Molecular Weight
32 kDa
Species
Human
Available Sizes
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items