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Recombinant Human DYNLL1 Protein (His Tag)

Product Specifications

Background

Human Dynein Cytoplasmic Light Chain 1 (DYNLL1) has been identified as a protein that interacts with NOS1, leading to NOS1 inhibition. NOS1 dimer is destabilized after binding DYNLL1 a conformation necessary activity, and it regulate numerous biologic processes throughits effects on nitric oxide synthase activity. DYNLL1 is widely expressed, with higher expression in testis and moderate expression in brain.

Abbreviation

DYNLL1

Synonyms

8 kDa Dynein Light Chain; DLC1; DLC8; DNCL1; DNCLC1; DYNLL1; Dynein Light Chain 1 Cytoplasmic; Dynein Light Chain LC8-Type 1; HDLC1 ; PIN; Protein Inhibitor of Neuronal Nitric Oxide Synthase

UniProt

P63167

Accession Number

P63167

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Gly89

Field of Research

Signal Transduction; Cell biology; Neuroscience; Cancer; epigenetics and nuclear signal; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Calculated Molecular Weight

12.5 kDa

Observed Molecular Weight

14 kDa

Species

Human

Available Sizes

Frequently Asked Questions

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