Recombinant Human CXCL12/SDF-1 Protein (aa19-93)
Product Specifications
Background
Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface; and can also bind syndecan4. SDF1 is known to influence lymphopoiesis; regulate patterning and cell number of neural progenitors; and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.
Abbreviation
CXCL12; SDF-1
Synonyms
C-X-C Motif Chemokine 12; CXCL12; IRH; Intercrine Reduced in Hepatomas; PBSF; Pre-B Cell Growth-Stimulating Factor; SDF-1; SDF1; SDF1A; SDF1B; Stromal Cell-Derived Factor 1; hIRH; hSDF-1
UniProt
P48061
Accession Number
P48061
Expression System
E.coli
Tag
None
Sequence
Ser19-Met93
Field of Research
Microbiology; Cardiovascular; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/ihoxmp
Product MSDS
https://789.bio/eb/TqH4mT
Calculated Molecular Weight
8.8 kDa
Observed Molecular Weight
12 kDa
Species
Human
Available Sizes
Curated Selection
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