Recombinant Human CXCL12/SDF-1 Protein (aa19-93)

Product Specifications

Background

Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1α and SDF1β are identical except for the four residues present in the C-terminus of SDF1β but absent from SDF1α. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface; and can also bind syndecan4. SDF1 is known to influence lymphopoiesis; regulate patterning and cell number of neural progenitors; and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.

Abbreviation

CXCL12; SDF-1

Synonyms

C-X-C Motif Chemokine 12; CXCL12; IRH; Intercrine Reduced in Hepatomas; PBSF; Pre-B Cell Growth-Stimulating Factor; SDF-1; SDF1; SDF1A; SDF1B; Stromal Cell-Derived Factor 1; hIRH; hSDF-1

UniProt

P48061

Accession Number

P48061

Expression System

E.coli

Tag

None

Sequence

Ser19-Met93

Field of Research

Microbiology; Cardiovascular; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.