Recombinant Human CXCL10 Protein
Product Specifications
Background
Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.
Abbreviation
CXCL10
Synonyms
10 kDa Interferon Gamma-Induced Protein; C-X-C Motif Chemokine 10; CXCL10; Gamma-IP10; INP10; IP-10; SCYB10; Small-Inducible Cytokine B10
UniProt
P02778
Accession Number
P02778
Expression System
E.coli
Tag
N-His
Sequence
Val22-Pro98
Applications
Cell culture
Field of Research
Cancer; immunology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 98 % as determined by reducing SDS-PAGE.
Bioactivity
Measure by its ability to chemoattract human PBMCs using a concentration range of 10.0 - 100.0 ng/mL. Note: Results may vary from different PBMC donors.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
9.5 kDa
Observed Molecular Weight
15 kDa
Species
Human
Available Sizes
Documents
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