Recombinant Human CXCL10 Protein

Product Specifications

Background

Human C-X-C Motif Chemokine Ligand 10 (CXCL10) is a non-ELR chemokine secreted by various cell types; such as monocytes; endothelial cells and fibroblasts; in response to IFN-γ. CXCL10 functions via chemokine receptor CXCR3. CXCL10 has been attributed to several roles; such as chemoattraction for activated T-lymphocytes; inhibition of angiogenesis; and antitumor activity.

Abbreviation

CXCL10

Synonyms

10 kDa Interferon Gamma-Induced Protein; C-X-C Motif Chemokine 10; CXCL10; Gamma-IP10; INP10; IP-10; SCYB10; Small-Inducible Cytokine B10

UniProt

P02778

Accession Number

P02778

Expression System

E.coli

Tag

N-His

Sequence

Val22-Pro98

Applications

Cell culture

Field of Research

Cancer; immunology

Endotoxin

< 0.1 EU per μg of the protein as determined by the LAL method.

Purity

> 98 % as determined by reducing SDS-PAGE.

Bioactivity

Measure by its ability to chemoattract human PBMCs using a concentration range of 10.0 - 100.0 ng/mL. Note: Results may vary from different PBMC donors.

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.