Recombinant Human CXCL1 Protein (His Tag)
Product Specifications
Background
Chemokine (C-X-C motif) Ligand 1 Protein (CXCL1) is a growth factor for melanoma cells and a chemotaxin for neutrophils and a member of the CXC chemokine family that is a potent neutrophil attractant and activator and is also active toward basophils. CXCL1 is expressed by macrophages, neutrophils and epithelial cells; it has neutrophil chemoattractant activity. CXCL1 plays a critical nonredundant role in the development of experimental Lyme arthritis and carditis via CXCR2-mediated recruitment of neutrophils into the site of infection and may also have important pro-nociceptive effects via its direct actions on sensory neurons, and may induce long-term changes that involve protein synthesis.
Abbreviation
CXCL1
Synonyms
C-X-C Motif Chemokine 1; CXCL1; GRO; GRO-Alpha (1-73) ; GRO1; GROA; Growth-Regulated Alpha Protein; MGSA; Melanoma Growth Stimulatory Activity; NAP-3; Neutrophil-Activating Protein 3; SCYB1
UniProt
P09341
Accession Number
P09341
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala35-Asn107
Field of Research
Immunology
Endotoxin
< 0.01 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
8.9 kDa
Observed Molecular Weight
10-14 kDa
Species
Human
Available Sizes
Documents
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