Recombinant Human CFHR2 Protein (His Tag)

Product Specifications

Background

Complement Factor H-Related Protein 2 (CFHR2) is a secreted protein that belongs to the complement factor H protein family. Members of the H-related protein family are exclusively composed of individually folded protein domains, termed short consensus repeats (SCRs) or complement control modules. CFHR2 is synthesized as a 270 amino acid precursor that contains an 18 amino acid signal peptide and a 252 amino acid mature chain with 4 Sushi (CCP/SCR) domains. CFHR2 is synthesized in the liver and secreted into plasma. It may be involved in complement regulation. CFHR2 can also be associated with lipoproteins and may play a role in lipid metabolism.

Abbreviation

CFHR2

Synonyms

CFHL2; CFHR2; Complement Factor H-Related Protein 2; DDESK59; FHR-2; FHR2; H Factor-Like 3; H Factor-Like Protein 2; HFL3

UniProt

P36980

Accession Number

P36980

Expression System

HEK293 Cells

Tag

C-His

Sequence

Glu19-Lys270

Field of Research

Signal Transduction; Cancer; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.