Recombinant Human Clusterin/ApoJ Protein (Fc & His Tag)

Product Specifications

Background

Clusterin is a secreted protein which belongs to the Clusterin family. Clusterin is expressed in adult testis; heart; ovary; adrenal gland; brain and liver. Clusterin has been suggested to be involved in several basic biological events such as cell death; tumor progression; and neurodegenerative disorders. In addition; Clusterin is up/ down regulated on the mRNA or protein level in many pathological and clinically relevant situations including cancer; organ regeneration; infection; Alzheimer disease; retinitis pigmentosa; myocardial infarction; renal tubular damage; autoimmunity and others.

Abbreviation

Clusterin; ApoJ

Synonyms

AAG4; APO-J; APOJ; Aging-Associated Gene 4 Protein; Apo-J; Apolipoprotein J; CLI; CLU; CLU1; CLU2; Clusterin; Complement Cytolysis Inhibitor; Complement-Associated Protein SP-40; KUB1; Ku70-Binding Protein 1; NA1/NA2; TRPM-2; Testosterone-Repressed Prostate Message 2

UniProt

P10909

Accession Number

P10909

Expression System

HEK293 Cells

Tag

C-Fc-His

Sequence

Asp23-Glu449

Field of Research

Signal Transduction; Cardiovascular; Cancer; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.