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Recombinant Human CELA3A Protein (His Tag)

Product Specifications

Background

Chymotrypsin-Like Elastase Family Member 3A (CELA3A) is an enzyme that contains one peptidase S1 domain. ELA3A belongs to the peptidase S1 family of the Elastase subfamily. ELA3A is secreted from the pancreas as a zymogen and, like other serine proteases such as trypsin, chymotrypsin and kallikrein, it has a digestive function in the intestine. ELA3A may also function in the intestinal transport and metabolism of cholesterol. ELA3A is efficient protease with alanine specificity but only little elastolytic activity. ELA3A preferentially cleaves proteins after alanine residues.

Abbreviation

CELA3A

Synonyms

CELA3A; Chymotrypsin-Like Elastase Family Member 3A; ELA3; ELA3A; Elastase IIIA; Elastase-3A; Protease E

UniProt

P09093

Accession Number

AAH07028.1

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ser16-His270

Field of Research

Signal Transduction; Cell biology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

28.9 kDa

Observed Molecular Weight

31 kDa

Formulation

Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5.

Species

Human

Available Sizes

Curated Selection

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