Recombinant Human CEACAM3/CD66d Protein (His Tag)

Product Specifications

Background

Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3 (CEACAM3) belongs to the immunoglobulin superfamily and CEA family. CEACAM3 was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM3 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, it is associated with the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.

Abbreviation

CEACAM3; CD66d

Synonyms

CD66D; CD66d; CEA; CEACAM3; Carcinoembryonic Antigen CGM1; Carcinoembryonic Antigen-Related Cell Adhesion Molecule 3; MGC119875; W264; W282

UniProt

P40198

Accession Number

P40198

Expression System

HEK293 Cells

Tag

C-His

Sequence

Lys35-Gly155

Field of Research

Tags & Cell Markers; Microbiology; Cancer; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.