Recombinant Human CD55/DAF Protein (His Tag)
Product Specifications
Background
CD55 is a member of the RCA (regulators of complement activation) family. RCA proteins is characterized by the presence of four to 30 SCRs (short consensus repeats also called CCPs for control protein modules) in their plasmaexposed regions. CD55 containing four SCR modules is involved in the regulation of the complement cascade. CD55 is known to bind CD97 via the first SCR. It also binds physiologically generated C3 convertases with its second and third SCRs. Binding results in an accelerated “decay”, or dissociation of active C3 convertases, thus blocking the development of C’ attack complexes on nonforeign cells. It is known that viruses and bacteria also utilize multiple SCR sites for infection.
Abbreviation
CD55; DAF
Synonyms
CD55; CR; CROM; Complement Decay-Accelerating factor; DAF; TC
UniProt
P08174
Accession Number
P08174
Expression System
HEK293 Cells
Tag
C-His
Sequence
Asp35-Ser353
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/t5tes8
Product MSDS
https://789.bio/eb/1Oefz5
Calculated Molecular Weight
36.0 kDa
Observed Molecular Weight
50-75 kDa
Species
Human
Available Sizes
Curated Selection
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