Recombinant Human TNFSF7/CD70 Protein (Fc Tag)
Product Specifications
Background
CD27 Ligand (CD70) is a 30 kDa type 2 transmembrane glycoproteinis that belongs to the tumor necrosis factor (TNF) ligand family.Human CD27 Ligand extracellular region is 64% aa identical to mouse and rat CD27 Ligand extracellular regions. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Abbreviation
TNFSF7; CD70
Synonyms
CD27 ligand; CD27L; CD27LG; CD70; CD70 antigen; TNFSF7; Tumor necrosis factor ligand superfamily member 7
UniProt
P32970
Accession Number
P32970
Expression System
HEK293 Cells
Tag
C-Fc
Sequence
Gln45-Pro193
Field of Research
Cancer; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/p4xmhg
Product MSDS
https://789.bio/eb/aLirnD
Calculated Molecular Weight
43.6 kDa
Observed Molecular Weight
52 kDa
Species
Human
Available Sizes
Curated Selection
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