Recombinant Human CCL3 Protein
Product Specifications
Background
Human Chemokine (C-C Motif) Ligand 3 (CCL3) is a small cytokine belonging to the CC chemokine family. CCL3 is primarily expressed in T cells, B cells, and monocytes after antigen or mitogen stimulation. CCL3 exhibits chemoattractive and adhesive effects on lymphocytes. CCL3 exerts multiple effects on hematopoietic precursor cells and inhibits the proliferation of hematopoietic stem cells in vitro as well as in vivo. CCR1 and CCR5 have been identified as functional receptors for CCL3.
Abbreviation
CCL3
Synonyms
C-C Motif Chemokine 3; CCL3; G0/G1 Switch Regulatory Protein 19-1; G0S19-1; MIP-1-Alpha; MIP1A; Macrophage Inflammatory Protein 1-Alpha; PAT 464.1; SCYA3; SIS-Beta; Small-Inducible Cytokine A3; Tonsillar Lymphocyte LD78 Alpha Protein
UniProt
P10147
Accession Number
P10147
Expression System
E.coli
Tag
None
Sequence
Ala 27-Ala 92
Applications
Cell culture
Field of Research
Immunology
Endotoxin
< 0.1 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measure by its ability to chemoattract human PBMC using a concentration range of 5 -50 ng/mL.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/zuqml0
Product MSDS
https://789.bio/eb/bbvnf9
Calculated Molecular Weight
8.4 kDa
Observed Molecular Weight
8-11 kDa
Species
Human
Available Sizes
Curated Selection
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