Recombinant Human CCL14/HCC-3 Protein (His Tag)

Product Specifications

Background

Chemokine (C-C motif) Ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.

Abbreviation

CCL14; HCC-3

Synonyms

C-C Motif Chemokine 14; CCL14; Chemokine CC-1/CC-3; HCC-1 (1-74) ; HCC-1/HCC-3; NCC-2; NCC2; SCYA14; Small-Inducible Cytokine A14

UniProt

Q16627

Accession Number

Q16627

Expression System

HEK293 Cells

Tag

C-His

Sequence

Thr 20-Asn93

Field of Research

Signal Transduction; Cancer; immunology; metabolism

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.