Recombinant Human Carbonic Anhydrase 5B/CA5B Protein (His Tag)
Product Specifications
Background
Carbonic Anhydrase 5B (CA5B) is a member of alpha-carbonic anhydrase family (CAs) that catalyze the reversible hydration of carbon dioxide. CAs is associated with many biological processes; including calcification; respiration; bone resorption; acid-base balance and the formation of aqueous humor. CA5B is highly expressed in heart; pancreas; kidney; placenta; lung; and skeletal muscle; but it is restricted to the liver. CA5B is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA; CA-VA. CA5B is inhibited by coumarins; sulfonamide derivatives such as acetazolamide (AZA) ; saccharin; and Foscarnet.
Abbreviation
Carbonic Anhydrase 5B; CA5B
Synonyms
CA-VB; CA5B; Carbonate Dehydratase VB; Carbonic Anhydrase 5B Mitochondrial; Carbonic Anhydrase VB
UniProt
Q9Y2D0
Accession Number
Q9Y2D0
Expression System
E.coli
Tag
C-His
Sequence
Cys34-Pro317
Field of Research
Signal Transduction; Tags & Cell Markers; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
33.8 kDa
Observed Molecular Weight
33 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 100mM NaCl, pH 8.0.
Species
Human
Available Sizes
Documents
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