Recombinant Human Carbonic Anhydrase 1/CA1 Protein (His Tag)
Product Specifications
Background
Carbonic Anhydrase 1 (CA1) is a cytosolic enzyme, belonging to the alpha-carbonic anhydrase family. It is highly expressed in erythrocytes and acts as an early marker for erythroid differentiation. Carbonic anhydrase 1 plays a improtant role in many biological processes such as calcification, cellular respiration, bone resorption, acid-base balance. It is activated by imidazole, histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine. At the same time, It is inhibited by sulfonamide derivatives and coumarins. In addition, CA1 is a zinc metalloenzyme that has reversible hydration of carbon dioxide. It can hydrate cyanamide to urea.
Abbreviation
Carbonic Anhydrase 1; CA1
Synonyms
CA-I; CA1; CAB; Carbonate Dehydratase I; Carbonic Anhydrase 1; Carbonic Anhydrase B; Carbonic Anhydrase I
UniProt
P00915
Accession Number
P00915
Expression System
E.coli
Tag
C-His
Sequence
Ala2-Phe261
Field of Research
Cell biology; Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
29.9 kDa
Observed Molecular Weight
25-35 kDa
Formulation
Supplied as a 0.2 μm filtered solution of 12.5mM Tris-HCl, 75mM NaCl, pH 7.5.
Species
Human
Available Sizes
Documents
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