Recombinant Human Calcitonin/CALCA Protein (His Tag)
Product Specifications
Background
Calcitonin is a secreted protein which belongs to the calcitonin family. Calcitonin is cleaved into the following two chains: Calcitonin and Katacalcin. Katacalcin is a potent plasma calcium-lowering peptide. Calcitonin is a 32-amino acid linear polypeptide hormone. Calcitonin acts to reduce blood calcium (Ca2+) ; opposing the effects of parathyroid hormone (PTH) . Its importance in humans has not been as well established as its importance in other animals; as its function is usually not significant in the regulation of normal calcium homeostasis. Calcitonin causes a rapid but short-lived drop in the level of calcium and phosphate in blood by promoting the incorporation of those ions in the bones.
Abbreviation
Calcitonin; CALCA
Synonyms
CALC1; CALCA; CCP; Calcitonin; Calcitonin Carboxyl-Terminal Peptide; Katacalcin; PDN-21
UniProt
P01258
Accession Number
P01258
Expression System
HEK293 Cells
Tag
C-His
Sequence
Ala26-Asn141
Field of Research
Signal Transduction; Cardiovascular; Neuroscience; Cancer
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
13.8 kDa
Observed Molecular Weight
16 kDa
Species
Human
Available Sizes
Curated Selection
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