Recombinant Human Calcineurin B/CNB Protein (His Tag)

Product Specifications

Background

Calcineurin Subunit B Type 1 belongs to the calcineurin regulatory subunit family. Calcineurin Subunit B Type 1 is a Ser/Thr-specific calcium and calmodulin-dependent protein phosphatase. It is composed of a catalytic subunit (A) and a regulatory subunit (B) . It contains four EF-hand domains and four functional calcium-binding sites. Calcineurin Subunit B Type 1 plays an improtant role in the T cell activation pathway.

Abbreviation

Calcineurin B; CNB

Synonyms

CNA2; CNB; Calcineurin Subunit B Type 1; PPP3R1; Protein Phosphatase 2B Regulatory Subunit 1; Protein Phosphatase 3 Regulatory Subunit B Alpha Osoform 1

UniProt

P63098

Accession Number

P63098

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Val170

Field of Research

Signal Transduction; immunology

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.