Recombinant Human BCAS2/DAM1 Protein (His & T7 Tag)
Product Specifications
Background
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator and is capable of enhancing ER-mediated transcription.
Abbreviation
BCAS2; DAM1
Synonyms
BCAS2; Breast Carcinoma-Amplified Sequence 2; DAM1; DNA Amplified in Mammary Carcinoma 1 Protein; Pre-mRNA-Splicing Factor SPF27; Spliceosome-Associated Protein SPF 27
UniProt
O75934
Accession Number
O75934
Expression System
E.coli
Tag
N-T7 & C-His
Sequence
Ala2-Phe225
Field of Research
Tags & Cell Markers; epigenetics and nuclear signal
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
28.6 kDa
Observed Molecular Weight
60 kDa
Species
Human
Available Sizes
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