Recombinant Human Apolipoprotein H/ApoH Protein (His Tag)
Product Specifications
Background
Apolipoprotein H (ApoH) is a 50 kDa variably glycosylated member of the complement control superfamily of proteins. Human ApoH is a major phospholipid binding protein and an important component to measure in the assessment of anti-phospholipid syndrome. Hepatocyte-derived ApoH binds to negatively charged phospholipids . It circulates as a component of lipoprotein particles and as a lipid-free serum protein. Human ApoH is also more specific than anti-cardiolipin antibodies and its presence correlates better with thrombotic risk. Mature human ApoH shares 76% and 82% aa sequence identity with mouse and rat ApoH.
Abbreviation
Apolipoprotein H; ApoH
Synonyms
APC inhibitor; APOH; Activated Protein C-Binding Protein; Anticardiolipin Cofactor; Apo-H; Apolipoprotein H; B2G1; B2GP1; B2GPIBeta (2) GPI; BG; Beta-2-Glycoprotein 1; Beta-2-Glycoprotein I
UniProt
P02749
Accession Number
P02749
Expression System
HEK293 Cells
Tag
C-His
Sequence
Gly20-Ser345
Field of Research
Signal Transduction; Cardiovascular; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
37.3 kDa
Observed Molecular Weight
45-70 kDa
Species
Human
Available Sizes
Documents
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