Recombinant Human Annexin A8/ANXA8 Protein
Product Specifications
Background
Annexin A8 (ANXA8) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A8 contains 4 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA8 is preferentially expressed in acute promyelocytic leukemia (APL) cells, which suggests its participation in hematopoietic cell differentiation. In addition, ANXA8 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade.
Abbreviation
Annexin A8; ANXA8
Synonyms
ANX8; ANXA8; Annexin A8; Annexin VIII; Annexin-8; VAC-Beta; Vascular Anticoagulant-Beta
UniProt
P13928
Accession Number
P13928
Expression System
E.coli
Tag
None
Sequence
Met 1-Pro327
Field of Research
Signal Transduction; Cardiovascular
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/tdhayh
Product MSDS
https://789.bio/eb/ujDenD
Calculated Molecular Weight
36.9 kDa
Observed Molecular Weight
36 kDa
Species
Human
Available Sizes
Curated Selection
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