Recombinant Human Annexin A6/ANXA6 Protein (His Tag)

Product Specifications

Background

Annexin A6 (ANAX6) belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Annexin A6 is a secreted protein and locates on the cell surface. Annexin A6 contains 8 annexin repeats separated by linking sequences of variable lengths. A pair of annexin repeats may form one binding site for calcium and phospholipid. ANXA6 is involved in the regulation of the release of Ca2+ from intracellular stores and may be associated with CD21. In addition, ANXA6 has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.

Abbreviation

Annexin A6; ANXA6

Synonyms

67 kDa Calelectrin; ANX6; ANXA6; Annexin A6; Annexin VI; Annexin-6; CPB-II; Calphobindin-II; Chromobindin-20; Lipocortin VI; Protein III; p68; p70

UniProt

P08133

Accession Number

P08133

Expression System

E.coli

Tag

C-His

Sequence

Ala2-Asp673

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.