Recombinant Human Annexin A3/ANXA3 Protein

Product Specifications

Background

Annexin A3 (ANXA3) contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. it also also play a role in anti-coagulant properties.

Abbreviation

Annexin A3; ANXA3

Synonyms

2-cyclic phosphate 2-phosphohydrolase;35-alpha calcimedin; ANX3; Annexin III; Annexin-3; Inositol 1; Lipocortin III; PAP-III; Placental anticoagulant protein III

UniProt

P12429

Accession Number

P12429

Expression System

E.coli

Tag

None

Sequence

Met 1-Asp323

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.