Recombinant Human Annexin A2/ANXA2 Protein

Product Specifications

Background

Annexin A2 (ANXA2) is a member of the annexin family and has roles in the regulation of cellular growth and in signal transduction pathways. ANXA2 protein is associated with sickle cell osteonecrosis and the expression reduce of ANXA2 is associated with osteosarcoma metastases. ANXA2 functions as an autocrine factor, it can increases osteoclast formation and bone resorption. ANXA2 is involved in muscular dystrophies. In humans, the up-regulation of ANXA2 is related with colon adenocarcinoma cell differentiation.

Abbreviation

Annexin A2; ANXA2

Synonyms

ANX2; ANX2L4; ANXA2; Annexin A2; Annexin II; Annexin-2; CAL1H; Calpactin I Heavy Chain; Calpactin-1 Heavy Chain; Chromobindin-8; LPC2D; Lipocortin II; PAP-IV; Placental Anticoagulant Protein IV; Protein I; p36

UniProt

P07355

Accession Number

P07355

Expression System

E.coli

Tag

None

Sequence

Ser2-Asp339

Field of Research

Signal Transduction

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.