Recombinant Human ASB13 Protein (His Tag)
Product Specifications
Background
Ankyrin repeat and SOCS box protein 13 (ASB13) is a member of the ankyrin repeat and SOCS box-containing (ASB) family. ASB13 contain six ankyrin repeats sequence and a SOCS box domain. The SOCS box serves to couple suppressor of cytokine signalling (SOCS) proteins and their binding partners with the elongin B and C complex, possibly targeting them for degradation. ASB13 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Abbreviation
ASB13
Synonyms
ASB13; Ankyrin repeat and SOCS box protein 13
UniProt
Q8WXK3
Accession Number
Q8WXK3
Expression System
E.coli
Tag
N-His
Sequence
Met 1-Asn278
Field of Research
Cell biology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
31.4 kDa
Observed Molecular Weight
28 kDa
Formulation
Supplied as a 0.2 μm filtered solution of PBS, 4M Urea, pH 7.4.
Species
Human
Available Sizes
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