Recombinant Human APBA3 Protein (His Tag)
Product Specifications
Background
Amyloid β A4 Precursor Protein-Binding Family A Member 3 (APBA3) is an adapter protein that belongs to the X11 family. APBA3 contains 2 PDZ (DHR) domains and 1 PID domain and interacts with the Alzheimer's disease amyloid precursor protein.. APBA3 is believed to be involved in signal transduction processes. Unlike X11-α and -β which are generally neuronal proteins, APBA3 is widely expressed in all tissues examined with lower levels in brain and testis. It binds to the cytoplasmic domain of amyloid protein (APP) in vivo and may modulate processing of the β-amyloid precursor protein (APP) and hence formation of β-APP.
Abbreviation
APBA3
Synonyms
APBA3; Adapter protein X11Gamma; Amyloid Beta A4 Precursor Protein-Binding Family A Member 3; MINT3; Mint-3; Neuron-Specific X11L2 Protein; Neuronal Munc18-1-Interacting Protein 3; X11L2
UniProt
O96018
Accession Number
O96018
Expression System
E.coli
Tag
C-His
Sequence
Met 1-Leu138
Field of Research
Neuroscience
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/du1kzs
Product MSDS
https://789.bio/eb/W5mTWL
Calculated Molecular Weight
15.5 kDa
Observed Molecular Weight
20 kDa
Species
Human
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
