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Recombinant Human Placental Alkaline Phosphatase 1/ALPP Protein (His Tag)

Product Specifications

Background

ALPP is a membrane protein and exits as a homodimer. ALPP is expressed only in normal term placenta, endocervix and fallopian tube and also in ovarian and proximal gastrointestinal tumors. It has been shown to play a role in a number of processes including cell signaling, long-term potentiation, and cell adhesion, however, the best known and most commonly studied role is implicated in Alzheimer's research.

Abbreviation

ALPP

Synonyms

ALPP and PLAP; Alkaline phosphatase; Alkaline phosphatase Regan isozyme; Placental alkaline phosphatase 1; placental type

UniProt

P05187

Accession Number

P05187

Expression System

HEK293 Cells

Tag

C-His

Sequence

Ile23-Asp506

Field of Research

Tags & Cell Markers; Cell biology; Cancer

Endotoxin

< 1.0 EU per μg of the protein as determined by the LAL method.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Not Applicable

Shipping Conditions

This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Storage Conditions

Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Calculated Molecular Weight

53.7 kDa

Observed Molecular Weight

60-85 kDa

Formulation

2

Species

Human

Available Sizes

Curated Selection

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