Recombinant Human IL-12 p40/IL-12B Protein

Interleukin-12 subunit beta (IL-12B) belongs to the type I cytokine receptor family. It contains 1 fibronectin type-III domain and 1 Ig-like C2-type domain. IL-12B is a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. IL-12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor encoded by IL12B and a 35 kD subunit encoded by IL12A. IL12 is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. It has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

IL-12/IL-23 p; IL-12 subunit p; NK cell stimulatory factor chain; NK cell Stimulating Factor Chain; CLMF p; IMD; IL12B; CLMF; CLMF2; IL-12B; IMD28; IMD29; NKSF; NKSF2; Cytotoxic lymphocyte maturation factor 40 kDa subunit; Cytotoxic Lymphocyte Maturation Factor 40 kDa subunit (CLMF p40) ; IL-12/IL-23 p40; NK cell Stimulating Factor Chain 2; p40; Interleukin-12 subunit beta; CLMF p40; IL-12 subunit p40; NK cell stimulatory factor chain 2; IL 12B; IL12 p40; Interleukin 12 beta chain; Interleukin 12 p40

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.