Recombinant Human LILRB4/CD85k/ILT3 Protein (aa 1-257, Fc Tag)
Product Specifications
Background
The leukocyte immunoglobulin-like receptor (LILR) B4 belongs to a family of cell surface receptors that possesses cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) . LILRB4 is believed to down-regulate activation signals mediated by non-receptor tyrosine kinase cascades through the recruitment of SHP-1. LILRB4 is associated with the pathological processes of various inflammatory diseases.The LILRB4 is a central inhibitory receptor in uterine dendritic cells (uDCs) that plays essential immune-regulatory roles at the maternal-fetal interface.
Synonyms
CD85K; ILT-3; ILT3; LIR-5; LIR5
UniProt
Q8NHJ6
Accession Number
NP_001265356.2
Expression System
HEK293 Cells
Tag
C-hFc
Sequence
Met 1-His257
Field of Research
Cardiovascular; epigenetics and nuclear signal; immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/0cxaah
Product MSDS
https://789.bio/eb/5OO80G
Calculated Molecular Weight
52.8 kDa
Species
Human
Available Sizes
Curated Selection
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