Recombinant Human IL36G/IL1F9 Protein (aa 18-169, His Tag)

Vaccinia H1-related phosphatase (VHR) is classified as a dual-specificity phosphatase (DUSP) ; and the other name is dual-specificity phosphatase 3 (DUSP3) . DUSPs are a heterogeneous group of protein phosphatases that can dephosphorylate both phosphotyrosine and phosphoserine/phosphothreonine residues within the one substrate. Unlike typical DUSPs; VHR lacks mitogen-activated protein kinase (MAPK) -binding domain; and shows poor activity against MAPKs. VHR often act on bisphosphorylated protein substrates; it displays a strong preference for dephosphorylating phosphotyrosine residues over phosphothreonine residues. VHR has been identified as a novel regulator of extracellular regulated kinases (ERKs) . VHR is responsible for the rapid inactivation of ERK following stimulation and for its repression in quiescent cells. VHR is a negative regulator of the Erk and Jnk pathways in T cells and; therefore; may play a role in aspects of T lymphocyte physiology that depend on these kinases.

UNQ; PRO; IL1F; IL1H; IL-1-related protein; Interleukin-1 homolog; IL-1F; IL-1H; IL1RP; IL-1RP; IL36G; IL-1F9; IL-1H1; IL-1RP2; IL1E; IL1F9; IL1H1; IL1RP2; IL-1 epsilon; IL-1-related protein 2; Interleukin-1 homolog 1; Interleukin-36 gamma; UNQ2456; PRO5737

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.