Recombinant Human CD32b/FCGR2B Protein (HEK293 Cells, His Tag)

Processing of the N-terminal initiator methionine or formylated methionine is an essential cellular process conserved from prokaryotes to eukaryotes. The proteolytic removal of N-terminal methionine from nascent peptides is catalyzed by a family of enzymes known as methionine aminopeptidases (MetAPs) and is essential for cell growth. METAP1 and METAP2 have different substrate specificity due to the differences in both size and shape of the active sites. As a member of the M24 family of metalloproteases, METAP1 plays an important role in G (2) /M phase regulation of the cell cycle and may serve as a promising target for the discovery and development of new anticancer agents.

CD32; CDw32; FCG2; FCGR2B; Fc-Gamma RII-b; Fc-Gamma-RIIb; FcRII-b; IGFR2; IgG Fc Receptor II-b; Low Affinity Immunoglobulin Gamma Fc Region Receptor II-b

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.