Recombinant Human PPM1G/PP2C-gamma Protein (aa 317-546, His Tag)
Product Specifications
Background
Protein phosphatase 1G; also known as Protein phosphatase 1C; Protein phosphatase 2C isoform gamma; Protein phosphatase magnesium-dependent 1 gamma; PP2C-gamma; PPM1G and PPM1C; is a cytoplasm protein which belongs to thePP2C family. PPM1G / PP2C-gamma is widely expressed. It is most abundant in testis; skeletal muscle; and heart. Alternatively spliced transcript variants encoding the same protein have been described. PP2C family members are known to be negative regulators of cell stress response pathways. PPM1G / PP2C-gamma is found to be responsible for the dephosphorylation of Pre-mRNA splicing factors; which is important for the formation of functional spliceosome. PPM1G / PP2C-gamma also plays a role in regulating cell cycle progression.
Synonyms
PP2C-Gamma; PP2CG; PP2CGAMMA; PPM1G; Protein Phosphatase 1C; Protein Phosphatase 1G; Protein Phosphatase 2C Isoform Gamma; Protein Phosphatase Magnesium-Dependent 1 Gamma
UniProt
O15355
Accession Number
O15355
Expression System
E.coli
Tag
N-His
Sequence
Met 317-Asp 546
Field of Research
Signal Transduction; Cell biology; epigenetics and nuclear signal
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
26.6 kDa
Observed Molecular Weight
30 kDa
Species
Human
Documents
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