Recombinant Human SAA4 Protein (GST Tag)
Product Specifications
Background
SAA4 is a member of the SAA family.SAA proteins are family of apolipoproteins of high density lipoprotein (HDL) . They can be separated into two distinct groups. First group (SAA1; SAA2; and SAA3) consists of acute phase reactant whose expression level increase in the blood in a response to trauma; infection; inflammation; and neoplasia. These acute phase SAAs associates with HDL during inflammation and remodel the HDL particle by displacing Apo-A1. The second distinct group consists of SAA4 and SAA5 which exist as the minor apolipoproteins on HDL; but this group of SAA constitutes more than 90% of all the SAA during homeostasis; and it is thought to play a role in the normal functioning of the HDL particle. SAA4 is a constitutively expressed protein which expressed only in humans and mice.It is connected almost completely with lipoproteins of the high density range. The physiological function of SAA4 is unknown; and its serum concentration has no association with those of other major apolipoproteins.
Synonyms
C-SAA; CSAA; Constitutively Expressed Serum Amyloid A Protein; SAA4; Serum Amyloid A-4 Protein
UniProt
P35542
Accession Number
P35542
Expression System
E. coli
Tag
N-GST
Sequence
Glu19-Tyr130
Field of Research
Cardiovascular; Cancer; metabolism
Endotoxin
Please contact us for more information.
Purity
> 93 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
39.8 kDa
Observed Molecular Weight
36 kDa
Formulation
Lyophilized from sterile PBS, 0.5% Triton X-100, pH 7.4<br/>Normally 5% - 8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Species
Human
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items