Recombinant Human CHST11/C4ST-1 Protein (His Tag)
Product Specifications
Background
CHST11, also known as C4ST-1, belongs to the sulfotransferase 2 family. CHST11 localizes to the golgi membrane, and catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of chondroitin. Chondroitin sulfate constitutes the predominant proteoglycan present in cartilage, and is distributed on the surfaces of many cells and extracellular matrices. A chromosomal translocation involving CHST11 gene and IgH, t (12;14) (q23; q32), has been reported in a patient with B-cell chronic lymphocytic leukemia.
Synonyms
C4ST; C4ST-1; C4ST1; HSA269537
UniProt
Q9NPF2
Accession Number
Q9NPF2-2
Expression System
Baculovirus-Insect Cells
Tag
C-His
Sequence
Met36-Glu347
Field of Research
Signal Transduction, Metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
38.4 kDa
Observed Molecular Weight
43 kDa
Species
Human
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