Recombinant Human UBE2D1 Protein (His Tag)

Product Specifications

Background

Ubiquitin-conjugating enzyme E2 D1 (UBE2D1) ; a member of human E2 ubiquitin-conjugating enzymes; is closely related to SFT; which is short for stimulator of iron (Fe) transport. In other words; UbcH5A is significantly up-regulated in the liver of iron-overloaded patients with hereditary hemochromatosis; as previously published for SFT. Moreover; a complex of UBE2D1 is critical in maintaining KRAS protein stability and propose that targeting such complex may be a unique strategy to degrade mutant KRAS to kill cancer cells.

Synonyms

SFT; Stimulator of Fe transport; UBC4/5 homolog; UBC5A; UBCH5; UBCH5A; UbcH5; Ubiquitin carrier protein D1; Ubiquitin-conjugating enzyme E2 D1; Ubiquitin-conjugating enzyme E2 (17) KB 1; Ubiquitin-conjugating enzyme E2-17 kDa 1; Ubiquitin-protein ligase D1

UniProt

P51668

Accession Number

P51668

Expression System

E.coli

Tag

N-His

Sequence

Ala 2-Met 147

Field of Research

Cell biology; epigenetics and nuclear signal

Endotoxin

Please contact us for more information.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.