Recombinant Human RGMA Protein (HEK293 Cells, His Tag)
Product Specifications
Background
RGMa; also known as RGM domain family; member A; belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. It helps guide Retinal Ganglion Cell (RGC) axons to the tectum in the midbrain. RGMa has been implicated to play an important role in the developing brain and in the scar tissue that forms after a brain injury. This protein may also function as a tumor suppressor in some cancers.
Synonyms
RGM; RGM domain family member A; Repulsive guidance molecule A
UniProt
Q96B86
Accession Number
NP_064596.2
Expression System
HEK293 Cells
Tag
C-His
Sequence
Met 1-Gly 422
Field of Research
Neuroscience; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/1og0cg
Product MSDS
https://789.bio/eb/KGqLqT
Calculated Molecular Weight
43.0 kDa
Observed Molecular Weight
36 kDa
Species
Human
Curated Selection
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