Recombinant Human ULBP2/N2DL-2 Protein (Fc Tag)
Product Specifications
Background
NKG2D ligand 2; also known as N2DL-2; NKG2DL2; ALCAN-alpha; Retinoic acid early transcript 1H; UL16-binding protein 2; ULBP2 and N2DL2; is cell membrane protein which belongs to theMHC class I family. ULBP2 / N2DL-2 is expressed in various types of cancer cell lines and in the fetus; but not in normal tissues. ULBP2 / N2DL-2 is a ligand for the NKG2D receptor; together with at least ULBP1 and ULBP3. ULBPs activate multiple signaling pathways in primary NK cells; resulting in the production of cytokines and chemokines. Binding of ULBPs ligands to NKG2D induces calcium mobilization and activation of the JAK2; STAT5; ERK and PI3K kinase/Akt signal transduction pathway.
Synonyms
ALCAN-Alpha; N2DL-2; N2DL2; NKG2D Ligand 2; NKG2DL2; RAET1H; Retinoic Acid Early Transcript 1H; UL16-Binding Protein 2; ULBP2
UniProt
Q9BZM5
Accession Number
Q9BZM5
Expression System
HEK293 Cells
Tag
C-hFc
Sequence
Met 1-Ser 217
Field of Research
Immunology
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Product Datasheet
https://789.bio/ea/c0lay1
Product MSDS
https://789.bio/eb/CWb1u1
Calculated Molecular Weight
48.7 kDa
Observed Molecular Weight
58 kDa
Species
Human
Curated Selection
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