Recombinant Human UBE2T Protein (His Tag)

Product Specifications

Background

Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers; representing an attractive target for the development of inhibitors. Notably; UBE2T locates at 1q32.1; and the gain of 1q is frequently observed in a variety of cancers. For instance; UBE2T serves an important role in the growth of bladder cancer cells; and may be considered as a potential biomarker and therapeutic target for bladder cancer.

Synonyms

Cell Proliferation-Inducing Gene 50 Protein; UBE2T; Ubiquitin Carrier Protein T; Ubiquitin-Conjugating Enzyme E2 T; Ubiquitin-Protein Ligase T

UniProt

Q9NPD8

Accession Number

Q9NPD8

Expression System

E.coli

Tag

C-His

Sequence

Met 1-Val197

Field of Research

Cell biology; epigenetics and nuclear signal

Endotoxin

Please contact us for more information.

Purity

> 90 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.