Recombinant Human LMAN2/VIP36 Protein (E.coli, His Tag)

Product Specifications

Background

The L-type lectin LMAN2 (also known as VIP36) appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport along the exosomal pathway. This may occur due to interference with the adaptor protein GGA1-mediated trans Golgi network-to-endosome transport of GPRC5B.A Golgi-traversing pathway for exosomal release of the cargo protein GPRC5B in which CD2AP facilitates the entry and LMAN2 impedes the exit of the flux; respectively.

Synonyms

C5orf8; Glycoprotein GP36b; LMAN2; Lectin Mannose-Binding 2; VIP36; Vesicular Integral-Membrane Protein 36; Vesicular Integral-Membrane Protein VIP36

UniProt

Q12907

Accession Number

Q12907

Expression System

E.coli

Tag

C-His

Sequence

As p45-Arg 322

Field of Research

Signal Transduction

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.