Recombinant Human BLBP/FABP7 Protein
Product Specifications
Background
BLBP; also known as FABP7; is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a family of small; highly conserved; cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP7 binds DHA with the highest affinity among all of the FABPs. FABPs may play roles in fatty acid uptake; transport; and metabolism. BLBP is expressed; during development; in radial glia by the activation of notch receptors. It was shown that reelin induces FABP7 expression in neural progenitor cells via notch-1 activation. BLBP variation is linked to weak prepulse inhibition (PPI) in mice and deficit in PPI is an endophenotypic trait observed in schizophrenia patients and their relatives.
Synonyms
B-FABP; BLBP; Brain Lipid-Binding Protein; Brain-Type Fatty Acid-Binding Protein; FABP7; FABPB; Fatty Acid-Binding Protein 7; Fatty Acid-Binding Protein Brain; MRG; Mammary-Derived Growth Inhibitor Related
UniProt
O15540
Accession Number
O15540
Expression System
E.coli
Tag
None
Sequence
Met 1-Ala132
Field of Research
Signal Transduction; Neuroscience; Cancer; metabolism
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.9 kDa
Observed Molecular Weight
16 kDa
Species
Human
Documents
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