Recombinant Human Tetherin/BST2 Protein (Fc Tag)
Product Specifications
Background
CLM-9; also known as TREM4; is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils; monocyte/macrophages; microglia; and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart; skeletal muscle; and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.
Synonyms
BST-2; BST2; Bone Marrow Stromal Antigen 2; CD317; HM1.24 Antigen; Tetherin
UniProt
Q10589
Accession Number
Q10589
Expression System
HEK293 Cells
Tag
N-hFc
Sequence
Asn49-Ser160
Field of Research
Signal Transduction; Tags & Cell Markers; Cardiovascular; epigenetics and nuclear signal; immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
41.0 kDa
Observed Molecular Weight
51 kDa
Species
Human
Documents
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