Recombinant Human PTH2/PTRH2 Protein (His Tag)
Product Specifications
Background
PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.
Synonyms
BIT1; CFAP37; CGI-147; IMNEPD; PTH; PTH 2; PTH2; PTRH2
UniProt
Q9Y3E5
Accession Number
Q9Y3E5
Expression System
E.coli
Tag
N-His
Sequence
Gly63-Tyr179
Field of Research
Cell biology; Cancer; epigenetics and nuclear signal; metabolism
Endotoxin
Please contact us for more information.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
14.5 kDa
Observed Molecular Weight
14 kDa
Species
Human
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