Recombinant Human PTH2/PTRH2 Protein (His Tag)

Product Specifications

Background

PTH2, also known as PTRH2, is a mitochondrial protein which belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. When in the cytoplasm, PTRH2 regulates the function of 2 transcriptional regulators, TLE5 and TLE1, thus promoting caspase-independent cell death.

Synonyms

BIT1; CFAP37; CGI-147; IMNEPD; PTH; PTH 2; PTH2; PTRH2

UniProt

Q9Y3E5

Accession Number

Q9Y3E5

Expression System

E.coli

Tag

N-His

Sequence

Gly63-Tyr179

Field of Research

Cell biology; Cancer; epigenetics and nuclear signal; metabolism

Endotoxin

Please contact us for more information.

Purity

> 95 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.