Recombinant Human IMP1/IMPA1 Protein (His Tag)

Product Specifications

Background

The IMPA1 gene product is responsible for the final step of biotransformation of inositol triphosphate and diacylglycerol, two second messengers. Despite its many physiological functions, no clinical phenotype has been assigned to this gene dysfunction to date. Additionally, IMPA1 is the main target of lithium, a drug that is at the forefront of treatment for bipolar disorder.

Synonyms

IMP 1; IMPA; IMPA1; IMPase 1; Inositol Monophosphatase 1; Inositol-1 (or 4) -Monophosphatase 1; Lithium-Sensitive Myo-Inositol Monophosphatase A1

UniProt

P29218

Accession Number

P29218-1

Expression System

E.coli

Tag

N-His

Sequence

Met 1-Asp277

Field of Research

Neuroscience, Signal Transduction

Endotoxin

Please contact us for more information.

Purity

> 85 % as determined by reducing SDS-PAGE.

Bioactivity

Not validated for activity

Reconstitution

Please refer to the printed manual for detailed information.

Shipping Conditions

This product is provided as lyophilized powder which is shipped with ice packs.

Storage Conditions

Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.