Recombinant Human CD3E & CD3G Heterodimer Protein
Product Specifications
Background
T-cell surface glycoprotein CD3 epsilon & CD3 gamma chain, also known as CD3E & CD3G, are single-pass type I membrane proteins. CD3D, together with CD3- epsilon (CD3E), CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
Synonyms
CD3E; CD3G Heterodimer; IMD18; T3E; TCRE
Accession Number
NP_000724.1&NP_000064.1
Expression System
HEK293 Cells
Tag
C-hFc-Flag & mFc Tag
Sequence
Met 1-Asp126&Met1-Ser116
Applications
ELISA
Field of Research
Immunology; Stem cells
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Measured by its ability to bind OKT3-mIgG2a in a functional ELISA.
Reconstitution
Please refer to the printed manual for detailed information.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
40.1&37.1 kDa
Observed Molecular Weight
42-47 kDa
Species
Human
Available Sizes
Documents
Frequently Asked Questions
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