Recombinant Human AKT2/PKB beta Protein (His & GST Tag)
Product Specifications
Background
AKT2 (AKT Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with AKT2 include Hypoinsulinemic Hypoglycemia With Hemihypertrophy and Diabetes Mellitus, Noninsulin-Dependent. Among its related pathways are Constitutive Signaling by AKT1 E17K in Cancer and RANK Signaling in Osteoclasts. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is AKT1.
Synonyms
HIHGHH; PKBB; PKBBETA; PRKBB; RAC-BETA
UniProt
P31751
Accession Number
NP_001617.1
Expression System
Baculovirus-Insect Cells
Tag
N-His-GST
Sequence
Met 1-Glu481
Field of Research
Signal Transduction; Cardiovascular; Neuroscience; Cancer; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
83.6 kDa
Formulation
Supplied as sterile solution of 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4
Species
Human
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