Recombinant Human CMPK1 Protein (His Tag)
Product Specifications
Background
CMPK1 plays a key role in the maintenance of pyrimidine nucleotide pool profile and for the metabolism of pyrimidine analogs in cells. It catalyzes the phosphoryl transfer from ATP to UMP, CMP, and deoxy-CMP (dCMP), resulting in the formation of ADP and the corresponding nucleoside diphosphate. CMPK1 also has a significant role in the activation of pyrimidine analogs, which are clinically useful anti-cancer and anti-viral drugs. In the meanwhile, CMPK1 functions in cellular nucleic acid biosynthesis.
Synonyms
CK; CMK; CMPK; UMK; UMP-CMPK; UMPK
UniProt
P30085
Accession Number
P30085
Expression System
Baculovirus-Insect Cells
Tag
N-His
Sequence
Met 1-Gly 196
Field of Research
Epigenetics and nuclear signal; metabolism
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 95 % as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
Not Applicable
Shipping Conditions
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.
Storage Conditions
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Calculated Molecular Weight
24.5 kDa
Observed Molecular Weight
27 kDa
Formulation
Supplied as sterile solution of 20mM Tris, 500mM Nacl, pH 7.4, 10% glycerol
Species
Human
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